Intervention Research to Improve Native American Health (IRNAH): R01 and R34 Notices of Funding Opportunity

https://cancercontrol.cancer.gov/native-american-intervention

Intervention Research to Improve Native American Health (IRINAH), a network of principal investigators and their partners, funded by the National Institutes of Health (NIH), was launched in 2011 through a program titled “Interventions for Health Promotion and Disease Prevention in Native American Populations.”

Despite tremendous strengths, Native populations have significantly varying rates of disease across many health outcomes such as chronic disease, substance use and addiction, cancer, mental illness, and sexually transmitted diseases. The IRINAH program was created to develop, adapt, and test the effectiveness of health-promotion and disease-prevention interventions in Native populations. Through this initiative, intervention and related research is sought to build upon community knowledge, resources, and resilience to identify and rigorously test culturally appropriate solutions to reduce morbidity and mortality. Research projects may address topics within the identified interests of any of the participating Institutes or Centers.

IRINAH has two Notices of Funding Opportunity (NOFOs)—an R01: PAR-25-379: Intervention Research to Improve Native American Health (R01 Clinical Trial Optional) and an R34: PAR-25-378: Intervention Research to Improve Native American Health (R34 Clinical Trial Optional). Applications are due October 21, 2026. The application deadline for AIDS/HIV-related research proposals is January 7 in 2026 and 2027.

For a list of Frequently Asked Questions, see here.


Questions?

Contact Dr. Sarah Vidal at sarah.vidal@nih.gov or Dr. Alexa Romberg at alexa.romberg@nih.gov.

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